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MPCCC Precision Oncology Seminars are an educational forum in which international and local guest speakers present different perspectives on the latest precision oncology research, clinical trials and treatment options.

Insights into the tumour immunopeptidome and its role in personalized immunotherapy

The use of mass spectrometry to characterise antigen presentation by cancer has undergone a revolution in recent years following the success of check point inhibition and the suggestion that post-therapy there are numerous immune targets revealed on the surface of cancers. I will discuss our approaches for the identification of different classes of antigens and how this information can be used to harness anti-tumour immune responses.


About the speaker

Professor Tony Purcell is an NHMRC Principal Research Fellow and Deputy Head (Research) of the Department of Biochemistry at Monash University. In addition, he is the vice president of the Australasian Proteomics Society and a council member of the Human Proteome Organisation (HUPO). His laboratory focuses on how the diverse array of peptides presented to the immune system, coined the immunopeptidome, is influenced by infection, inflammation and the environment. He has made important contributions to understanding the role of antigen presentation, including the characterizing T cell epitopes, in several autoimmune diseases, drug hypersensitivity, cancer and infectious diseasesHe is one of the most cited Australian proteomics researchers and a leader in the field of immunopeptidomics with over 230 related publications.


Event details

1.00-2.00pm, Friday 27 November

This event will be held online via Zoom. Zoom joining details will be released one hour before the commencement of the seminar.

Register for webinar here >>

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